Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss.

@article{Conroy2011LeptinAD,
  title={Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss.},
  author={Rushika M Conroy and Monica Girotra and Elizabeth Shane and Donald J McMahon and Katherine H. Pavlovich and Rudolph L. Leibel and Michael Rosenbaum and Judith Korner},
  journal={Metabolism: clinical and experimental},
  year={2011},
  volume={60 9},
  pages={
          1222-6
        }
}
The objective was to examine the effects of weight loss and leptin administration following weight loss on calciotropic hormones and bone turnover. This was a prospective, single-blinded study of 12 subjects (8 women, 4 men; 2 nonobese, 10 obese; age range, 19-46 years) who were studied on an inpatient basis while maintaining their usual weight [Wt(initial)] and during maintenance of 10% weight loss while receiving twice-daily injections of either a placebo [Wt(-10%P)] or replacement doses of… CONTINUE READING

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