Leptin Attenuates the Contractile Function of Adult Rat Cardiomyocytes Involved in Oxidative Stress and Autophagy.

@article{Luo2016LeptinAT,
  title={Leptin Attenuates the Contractile Function of Adult Rat Cardiomyocytes Involved in Oxidative Stress and Autophagy.},
  author={Liu-Jin Luo and Ying-Ping Liu and Xun Yuan and Gui-Ping Zhang and Ning Hou and Xiao-qian Wu and J. S. Luo and Gen-Shui Zhang},
  journal={Acta Cardiologica Sinica},
  year={2016},
  volume={32 6},
  pages={723-730}
}
BACKGROUND Leptin has been identified as an important protein involved in obesity. As a chronic metabolic disorder, obesity is associated with a high risk of developing cardiovascular and metabolic diseases, including heart failure. The aim of this paper was to investigate the effects and the mechanism of leptin on the contractile function of cardiomyocytes… CONTINUE READING