Lepromatous leprosy as a model of Schwann cell pathology and lysosomal activity.

@article{Dastur1979LepromatousLA,
  title={Lepromatous leprosy as a model of Schwann cell pathology and lysosomal activity.},
  author={Darab K. Dastur and G L Porwal},
  journal={Clinical and experimental neurology},
  year={1979},
  volume={16},
  pages={277-93}
}
A brief illustrated account is presented of the light microscopic pathology, histochemistry of lysosomal enzymes, and fine structural changes in the nerves of patients with untreated or treated lepromatous leprosy. Predominant bacillation of the Schwann cells of unmyelinated fibres, degeneration of their axons, prominence of phagolysosomes, and disappearance of these cells with endoneurial collagenosis were observed on electronmicroscopic examination of the index branch of the radial cutaneous… CONTINUE READING