• DOI:10.1016/S0960-894X(03)00153-7
Corpus ID: 19819078

Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus.

@article{Zhang2003LeporinBA,
  title={Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus.},
  author={Chaowei Zhang and Liang Jin and Belinda Mondie and S. Mitchell and A. Castelhano and W. Cai and N. Bergenhem},
  journal={Bioorganic & medicinal chemistry letters},
  year={2003},
  volume={13 8},
  pages={
          1433-5
        }
}

Chaowei Zhang, Liang Jin, +4 authors N. Bergenhem

Published 2003

Chemistry, Medicine

Bioorganic & medicinal chemistry letters

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Leporin B (1), a novel demethylated analogue of leporin A (2), was isolated from a taxonomically unidentified fungal strain as part of an effort to discover compounds with the ability to increase expression levels of the enzyme hexokinase II. The structure was determined by spectral methods, including 1D and 2D NMR, and HRMS. The relative stereochemistry was assigned by NOESY experiments and coupling constants.