Lentivirus-mediated estrogen receptor α overexpression in the central nervous system ameliorates experimental autoimmune encephalomyelitis in mice.

@article{Hu2013LentivirusmediatedER,
  title={Lentivirus-mediated estrogen receptor α overexpression in the central nervous system ameliorates experimental autoimmune encephalomyelitis in mice.},
  author={Xiao Sheng Hu and Xinyue Qin},
  journal={International journal of molecular medicine},
  year={2013},
  volume={31 5},
  pages={1209-21}
}
Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory cell infiltration of the central nervous system (CNS) and multifocal demyelination. Clinical data and clinical indicators demonstrate that estrogen improves the relapse-remittance of MS patients. This study aimed to investigate the anti-inflammatory effects and the underlying… CONTINUE READING