Lentivirus-mediated CD/TK fusion gene transfection neural stem cell therapy for C6 glioblastoma

Abstract

A suicide gene can convert nontoxic prodrugs into toxic products to kill tumor cells. In this study, our aim was to transfect lentivirus-mediated CD/TK fusion gene into Wistar rat’s neural stem cells (NSC) and then implant the NSC into a C6 glioma model to observe a C6 glioma growth inhibition effect. Primary NSC and stable transfection CD/TK fusion gene… (More)
DOI: 10.1007/s13277-013-0957-y

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