Lentiviral vectors: are they the future of animal transgenesis?

  title={Lentiviral vectors: are they the future of animal transgenesis?},
  author={Frank Park},
  journal={Physiological genomics},
  volume={31 2},
  • F. Park
  • Published 1 October 2007
  • Biology
  • Physiological genomics
Lentiviral vectors have become a promising new tool for the establishment of transgenic animals and the manipulation of the mammalian genome. While conventional microinjection-based methods for transgenesis have been successful in generating small and large transgenic animals, their relatively low transgenic efficiency has opened the door for alternative approaches, including lentiviral vectors. Lentiviral vectors are an appealing tool for transgenesis in part because of their ability to… 

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