Lentiviral Effector Pathways of TRIM Proteins.


The human tripartite motif (TRIM) family, composed of more than 77 members, encompasses an emerging group of innate antiviral factors. Most TRIM proteins are characterized by being E3 ubiquitin ligases, but also engage in specific interactions with a variety of cellular and viral partners. They are involved in many cellular processes, including cell… (More)
DOI: 10.1089/dna.2014.2374


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