Lentiginosis profusa syndrome. IV. Giant pigment granules (light microscopy).

Ionically separated epidermal sheets from pigmentations of two patients with lentiginosis profusa were incubated in dopa (3,4 dihydroxyphenylalanine) and slide-mounted. Light microscopy revealed intracellular giant pigment granules which appeared like those seen with von Recklinghausen's disease.