Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals

@article{Li1995LensEC,
  title={Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals},
  author={Win C. Li and Jerome R. Kuszak and Kelly L. Dunn and Ruiqi R Wang and Wenjian Ma and Guo-ming Wang and Abraham Spector and Mario Leib and Arthur M. Cotliar and Mordechai Weiss},
  journal={The Journal of Cell Biology},
  year={1995},
  volume={130},
  pages={169 - 181}
}
Cataract is a major ocular disease that causes blindness in many developing countries of the world. It is well established that various factors such as oxidative stress, UV, and other toxic agents can induce both in vivo and in vitro cataract formation. However, a common cellular basis for this induction has not been previously recognized. The present study of lens epithelial cell viability suggests such a general mechanism. When lens epithelial cells from a group of 20 cataract patients 12 to… CONTINUE READING

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