Lengthening contraction-induced inflammation is linked to secondary damage but devoid of neutrophil invasion.

@article{Lapointe2002LengtheningCI,
  title={Lengthening contraction-induced inflammation is linked to secondary damage but devoid of neutrophil invasion.},
  author={Beno{\^i}t M Lapointe and Jĕr{\^o}me Frenette and Claude H. C{\^o}t{\'e}},
  journal={Journal of applied physiology},
  year={2002},
  volume={92 5},
  pages={1995-2004}
}
Inflammation triggered by exercise-induced muscle damage (EIMD) has been postulated to influence the extent of tissue destruction. We tested the hypotheses that 1) repressing inflammation decreases secondary damage production and 2) EIMD leads to a sequential appearance of inflammatory cells in which neutrophil accumulation precedes macrophage invasion. Rat ankle dorsiflexor muscles were submitted to in situ lengthening contractions. Measurement of in vitro contractile properties, inflammatory… CONTINUE READING