Length of the acyl carbonyl bond in acyl-serine proteases correlates with reactivity.

Abstract

Resonance Raman (RR) spectroscopy has been used to obtain the vibrational spectrum of the acyl carbonyl group in a series of acylchymotrypsins and acylsubtilisins at the pH of optimum hydrolysis. The acyl-enzymes, which utilize arylacryloyl acyl groups, include three oxyanion hole mutants of subtilisin BPN', Asn155Leu, Asn155Gln, and Asn155Arg, and… (More)

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Cite this paper

@article{Tonge1990LengthOT, title={Length of the acyl carbonyl bond in acyl-serine proteases correlates with reactivity.}, author={Pauline Tonge and P R Carey}, journal={Biochemistry}, year={1990}, volume={29 48}, pages={10723-7} }