Length-dependent activation: its effect on the length-tension relation in cat ventricular muscle.

@article{Lakatta1977LengthdependentAI,
  title={Length-dependent activation: its effect on the length-tension relation in cat ventricular muscle.},
  author={Edward G. Lakatta and Brian R. Jewell},
  journal={Circulation research},
  year={1977},
  volume={40 3},
  pages={251-7}
}
In cat papillary muscles at 30 degrees C, bathed with Tyrode's solution containing 2.25 mM Ca2+, the effect of various inotropic interventions (varying the stimulus frequency and continual paired stimulation) on the shape of the steady state length-tension relation was examined at lengths from Lmax, where tension production is maximal, to 0.87 Lmax. The relative steepness of the length-tension curves for peak tension developed (DT) and for maximum rate of tension development (dT/dT) varied… CONTINUE READING

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Cardiac contractility: Do its determining factors interact (abstr)

  • A Manring, PAW Anderson, EA Johnson
  • Fed Proc
  • 1975
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