Lenalidomide in the treatment of multiple myeloma: a review

@article{Armoiry2008LenalidomideIT,
  title={Lenalidomide in the treatment of multiple myeloma: a review},
  author={Xavier Armoiry and G. Aulagner and Thierry Facon},
  journal={Journal of Clinical Pharmacy and Therapeutics},
  year={2008},
  volume={33}
}
Lenalidomide is an immunomodulatory drug derived from thalidomide. It was developed to maximize the anti‐inflammatory and anti‐neoplasic properties of thalidomide and to reduce its toxicity. The molecular mechanism of action of lenalidomide is unclear, but its therapeutic activity is mainly due to its well defined anti‐inflammatory, immunomodulatory, anti‐proliferative and anti‐angiogenic properties. In relapsed or refractory multiple myeloma (MM), lenalidomide, combined with standard dose… 

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Clinical Trials of Drug – Thalidomide, and Its Derivatives

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Characterization of haematological parameters with bortezomib–melphalan–prednisone versus melphalan–prednisone in newly diagnosed myeloma, with evaluation of long‐term outcomes and risk of thromboembolic events with use of erythropoiesis‐stimulating agents: analysis of the VISTA trial

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