Lenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis.

@article{McCarthy2017LenalidomideMA,
  title={Lenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis.},
  author={Philip L McCarthy and Sarah A. Holstein and Maria Teresa Petrucci and Paul G Richardson and Cyrille Hulin and Patrizia Tosi and Sara Bringhen and Pellegrino Musto and Kenneth C. Anderson and Denis Caillot and Francesca Gay and Philippe Moreau and G{\'e}rald Marit and Sin-Ho Jung and Zhinuan Yu and Benjamin Winograd and Robert D Knight and Antonio Palumbo and Michel Attal},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2017},
  volume={35 29},
  pages={
          3279-3289
        }
}
Purpose Lenalidomide maintenance therapy after autologous stem-cell transplantation (ASCT) demonstrated prolonged progression-free survival (PFS) versus placebo or observation in several randomized controlled trials (RCTs) of patients with newly diagnosed multiple myeloma (NDMM). All studies had PFS as the primary end point, and none were powered for overall survival (OS) as a primary end point. Thus, a meta-analysis was conducted to better understand the impact of lenalidomide maintenance in… CONTINUE READING
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