Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi.

@article{Kennedy2011LeishmanicidalAR,
  title={Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi.},
  author={M. L. Kennedy and F. Cort{\'e}s and J. Pi{\~n}ero and S. Castanys and A. L{\'o}pez-Arencibia and F. Gamarro and I. L. Bazzocchi and I. A. Jim{\'e}nez},
  journal={Planta medica},
  year={2011},
  volume={77 1},
  pages={
          77-80
        }
}
A new bicyclic diterpene with a labdane skeleton, 7-oxo-labd-8-en-15-ol ( 1), along with two known diterpenes and ten flavonoids were isolated from the leaves of Aeonium lindleyi (Crassulaceae). Their structures were elucidated on the basis of spectroscopic data, including 1D and 2D NMR experiments, and comparison with spectroscopic data reported in the literature. Labdan-8 α,15-diol (2) and labd-8(17)-en-3 β,15-diol (3) showed leishmanicidal activity against Leishmania tropica (IC (50) = 77.0… Expand
Anti-inflammatory Labdane Diterpenoids from Leonurus macranthus.
Phytochemical profile of the stems of Aeonium lindleyi
The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I.
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