Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia.

  title={Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia.},
  author={Christian Ferreira and Carlos L A Passos and Deivid C Soares and K{\^e}nia de P. Costa and Michelle Jakeline Cunha Rezende and Adriana Quintella Lob{\~a}o and {\^A}ngelo da Cunha Pinto and Lidilhone Hamerski and Elvira Maria Saraiva},
  journal={Experimental parasitology},
Leishmaniasis is caused by protozoan parasites belonging to the genus Leishmania and includes cutaneous, mucocutaneous and visceral clinical forms. The drugs currently available for leishmaniasis treatment are pentavalent antimonials, amphotericin B and miltefosine, which present high toxicity, elevated cost and development of parasite resistance. The natural products constitute an important source of substances with leishmanicidal potential. Here we evaluated in vitro the anti-Leishmania… Expand
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