Leishmanicidal activity of Yucatecan medicinal plants on Leishmania species responsible for cutaneous leishmaniasis.

@article{Getti2009LeishmanicidalAO,
  title={Leishmanicidal activity of Yucatecan medicinal plants on Leishmania species responsible for cutaneous leishmaniasis.},
  author={Giulia Getti and Priyanka Durgadoss and Dafne Dom{\'i}nguez-Carmona and Zhelmy Mart{\'i}n-Quintal and Sergio R Peraza-S{\'a}nchez and Luis Manuel Pe{\~n}a-Rodr{\'i}guez and David P Humber},
  journal={The Journal of parasitology},
  year={2009},
  volume={95 2},
  pages={456-60}
}
The leishmanicidal activity of 15 extracts and 4 pure metabolites obtained from Urechites andrieuxii, Colubrina greggii, Dorstenia contrajerva, and Tridax procumbens was evaluated using the newly developed MTS ({3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt) assay, optimized for promastigotes of Leishmania major, Leishmania tropica, and Leishmania aethiopica, as well as for L. aethiopica axenic amastigotes. The assay was then used for… CONTINUE READING