Leishmania major: promastigotes induce expression of a subset of chemokine genes in murine macrophages.

@article{Racoosin1997LeishmaniaMP,
  title={Leishmania major: promastigotes induce expression of a subset of chemokine genes in murine macrophages.},
  author={E L Racoosin and Stephen M Beverley},
  journal={Experimental parasitology},
  year={1997},
  volume={85 3},
  pages={283-95}
}
Recent studies suggest that Leishmania major promastigotes infect cultured macrophages in a stealthy fashion, activating little or no host gene expression and often interfering with the host's ability to respond to further stimulation. Here we examined macrophage transcription at early times following infection, when virulent parasites must execute steps required for survival. Stationary-phase promastigotes induced rapid and transient expression of transcripts of the chemokines JE (human MCAF… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 65 references

Leish - mania promastigotes selectively inhibit Interleukin 12 Induction in bone marrowderived macrophages from susceptible and resistant mice

  • J. A. Smith, R. T. GAZZINELLI, +4 authors D. L. SACKS
  • Journal of Experimental Medicine
  • 1996

ferential expression of chemokines in patients with localized and diffuse cutaneous American Leishmaniasis

  • U. RITTER, T. LASKAY, E.-B. BROCKER, O. VELAZCO, I. BECKER, R. GILLITZER
  • Journal of Infectious Diseases
  • 1996

Similar Papers

Loading similar papers…