Leishmania amazonensis infection: a comparison of in vivo leishmanicidal mechanisms between immunized and naive infected BALB/c mice.

@article{Pompeu1992LeishmaniaAI,
  title={Leishmania amazonensis infection: a comparison of in vivo leishmanicidal mechanisms between immunized and naive infected BALB/c mice.},
  author={Margarida Maria de Lima Pompeu and Luiz Ant{\^o}nio Rodrigues da Freitas and Maria Livia Santos and Aldina Barral and Manoel Barral-Netto},
  journal={Experimental parasitology},
  year={1992},
  volume={74 2},
  pages={169-76}
}
In vitro studies have shown that both macrophage activation and destruction of parasitized macrophages lead to leishmania destruction. The relative role played by such mechanisms in vivo have not been properly evaluated. We took advantage of the model of intravenous immunization with solubilized leishmanial antigen which renders partially resistant the… CONTINUE READING