Leishmania amazonensis: early proteinase activities during promastigote-amastigote differentiation in vitro.

@article{Alves2005LeishmaniaAE,
  title={Leishmania amazonensis: early proteinase activities during promastigote-amastigote differentiation in vitro.},
  author={Carlos Roberto Alves and Suzana C{\^o}rte-Real and Saulo Cabral Bourguignon and Carolina Machado de Sousa Chaves and Elvira Maria Breier Saraiva},
  journal={Experimental parasitology},
  year={2005},
  volume={109 1},
  pages={38-48}
}
Leishmania proteinase activity is known as parasite differentiation marker, and has been considered relevant for leishmanial survival and virulence. These properties suggest that Leishmania proteinases can be promising targets for development of anti-leishmania drugs. Here, we analyze the activities of four proteinases during the early phase of the Leishmania amazonensis promastigotes differentiation into amastigotes induced by heat shock. We have examined activities of cysteine-, metallo… CONTINUE READING