Leishmania Manipulation of Sand Fly Feeding Behavior Results in Enhanced Transmission

@article{Rogers2007LeishmaniaMO,
  title={Leishmania Manipulation of Sand Fly Feeding Behavior Results in Enhanced Transmission},
  author={Matthew E Rogers and Paul A. Bates},
  journal={PLoS Pathogens},
  year={2007},
  volume={3},
  pages={185 - 199}
}
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (<0.1%), even in areas of endemicity and high transmission. It has long since been assumed that the protozoan parasite Leishmania can manipulate the feeding behavior of its sand fly vector, thus enhancing transmission efficiency, but neither the way in which it does so nor the mechanisms behind such manipulation have been described. A key feature of parasite development in the sand fly gut is the… CONTINUE READING