Leishmania (Viannia) braziliensis: human mast cell line activation induced by logarithmic and stationary promastigote derived-lysates.

@article{Oliveira2005LeishmaniaB,
  title={Leishmania (Viannia) braziliensis: human mast cell line activation induced by logarithmic and stationary promastigote derived-lysates.},
  author={M P De Oliveira and Marcia Coronha Ramos Lima and Andrea Surrage Calheiros and Marco Aur{\'e}lio Martins and Paulo Renato Zuquim Antas and Paula Melo De Luca and Claude Pirmez},
  journal={Experimental parasitology},
  year={2005},
  volume={109 2},
  pages={72-9}
}
Herein we investigate the ability of live promastigotes and total lysate of Leishmania (Viannia) braziliensis, derived from parasites in the logarithmic (L-Lb) or stationary phase (S-Lb), to induce human mast cell line (HMC-1) activation. In comparison with medium-treated cells, a significant histamine release was observed in HMC-1 cultures stimulated with S-Lb. Lipophosphoglycan also induced histamine release by HMC-1 cells. In immunocytochemical assays, we found a marked staining for tryptase… CONTINUE READING