Legless pathogens: how bacterial physiology provides the key to understanding pathogenicity.

Abstract

This review argues that knowledge of microbial physiology and metabolism is a prerequisite to understanding mechanisms of pathogenicity. The ability of Neisseria gonorrhoeae to cope with stresses such as those found during infection requires a sialyltransferase to sialylate its lipopolysaccharide using host-derived CMP-NANA in the human bloodstream, the… (More)
DOI: 10.1099/mic.0.059048-0

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