Legionella pneumophila adaptation to intracellular life and the host response: Clues from genomics and transcriptomics

@article{Jules2007LegionellaPA,
  title={Legionella pneumophila adaptation to intracellular life and the host response: Clues from genomics and transcriptomics},
  author={Matthieu Jules and Carmen Buchrieser},
  journal={FEBS Letters},
  year={2007},
  volume={581}
}
Legionella pneumophila is the causative agent of the pneumonia‐like Legionnaires’ disease. The bacterium's survival and spread depend on the ability to replicate inside eukaryotic phagocytic cells. A particular feature of Legionella is its dual host system allowing the intracellular growth in protozoa like Acanthamoeba castellanii, and during infection in human alveolar macrophages. Genome analysis and comparisons as well as expression profiling of the pathogen and the host helped to identify… Expand
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