Legg‐Calvé‐Perthes Disease
@article{Kim2010LeggCalvPerthesD, title={Legg‐Calv{\'e}‐Perthes Disease}, author={Harry K.W. Kim}, journal={American Academy of Orthopaedic Surgeon}, year={2010}, volume={18}, pages={676–686} }
&NA; Legg‐Calvé‐Perthes disease is an idiopathic hip disorder that produces ischemic necrosis of the growing femoral head. Permanent femoral head deformity is the most significant sequela. Experimental studies indicate that the pathologic repair process, which is marked by an imbalance of bone resorption and formation, contributes to the pathogenesis of femoral head deformity. Important prognostic factors include degree of deformity, age at disease onset, extent of head involvement, head‐at…
65 Citations
Legg-calvé-perthes disease: Treatments
- Medicine
- 2014
Even though there is no resounding consensus of the best treatment of LCPD, there is an agreement on the primary goal of treatment – to maintain femoral head sphericity or minimize further deformity if already present.
Legg-Calvé-Perthes Disease
- MedicinePediatric Orthopedic Deformities, Volume 2
- 2019
The structural changes of the femoral head and acetabulum at skeletal maturity can vary from near normal to highly irregular, the more severe of which predispose the hip to degenerative arthritis in later years.
Legg-Calvé-Perthes disease
- Medicine
- 2015
A review of the newest available literature concerning the diagnosis and treatment of Legg-Calvé-Perthes disease in children and young adults focuses on the residual deformity characteristic of LCPD.
Arthrodiastasis for late onset Perthes' disease using a simple frame and limited soft tissue release: early results.
- MedicineActa orthopaedica Belgica
- 2011
Minimal soft tissue release and hip distraction can be regarded as a salvage procedure for late onset Perthes' disease with hip pain, at the stage of necrosis or fragmentation, with a statistically significant difference between pre and post-operative values.
Ischemic femoral head osteonecrosis in a piglet model causes three dimensional decrease in acetabular coverage
- MedicineJournal of orthopaedic research : official publication of the Orthopaedic Research Society
- 2018
It is indicated that the development of femoral head deformity following ischemic osteonecrosis produces specific and predictable changes to the shape of the acetabulum.
A Comparison of the Effectiveness of Surgical and Nonsurgical Treatment of Legg-Calve-Perthes Disease: A Review of the Literature
- MedicineAdvances in orthopedics
- 2012
Research provides some evidence to suggest that nontreatment of Legg-Calve-Perthes disease may be as effective as orthotic or surgical intervention, and more research is required to determine the effectiveness of orthotic and surgical treatment.
Childhood Femoral Head Osteonecrosis
- Medicine
- 2011
This review focuses on childhood FHO with a special attention to the conditions that are more commonly seen in the pediatric population: Legg-Calve-Perthes disease, corticosteroid-associated FHO, and sickle cell disease.
Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg‐Calvé‐Perthes' disease
- BiologyClinical anatomy
- 2016
An overview of the literature is presented, summarizing the current understanding of the pathogenesis, particularly related to how the formation of the vasculature to the femoral epiphysis places children aged 5–8 at a higher risk for Perthes' disease, and how skeletal immaturity and rostral sparing could increase the probability of developing Perthers' disease.
Legg‐Calvé‐Perthes Disease Produces Chronic Hip Synovitis and Elevation of Interleukin‐6 in the Synovial Fluid
- Medicine, BiologyJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- 2015
In the active stage of LCPD, chronic hip synovitis and significant elevation of IL‐6 are produced in the synovial fluid, and IL‐1β and TNF‐α levels were not elevated.
Clinical and genetic characteristics of Legg-Calve-Perthes disease
- MedicineJournal of Musculoskeletal Surgery and Research
- 2021
A better understanding of the association between LCPD and causative factors, for example, the role of hypercoagulability in osteonecrosis development, might lead to the development of improved treatments, to shorten the acute phase of the disease during childhood as well as to possibly reduce the long-term effects of osteoarthritis in adulthood.
References
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Evolution of Femoral Head Deformity During the Healing Phase of Legg‐Calvé‐Perthes Disease
- MedicineJournal of pediatric orthopedics
- 1993
The femoral head was more likely to undergo progressive flattening in older patients, in Those with more severe lateral pillar involvement, and in those with prolonged reossification.
Treatment of severe late-onset Perthes’ disease with soft tissue release and articulated hip distraction: revisited at skeletal maturity
- MedicineJournal of children's orthopaedics
- 2007
A combination of soft tissue release and joint distraction with a hinged mono-lateral external fixator for these patients with late-onset Perthes’ disease is used as a salvage procedure.
Valgus femoral osteotomy for hinge abduction in Perthes' disease. Decision-making and outcomes.
- MedicineThe Journal of bone and joint surgery. British volume
- 2004
Valgus osteotomy, with both rotational and sagittal correction, can improve symptoms, function and remodelling of the hip in patients with Perthes' disease.
Evaluation and treatment of young adults with femoro-acetabular impingement secondary to Perthes' disease.
- MedicineHip international : the journal of clinical and experimental research on hip pathology and therapy
- 2006
Hip pain and loss of motion in young adults with previous Legg-Calve-Perthes-Disease may be caused by anterior femoro-acetabular impingement, and correction of the femoral head/neck offset and treatment of the acetabular rim pathology was performed.
Legg-calve-perthes disease: a review of cases with onset before six years of age.
- MedicineThe Journal of bone and joint surgery. American volume
- 2007
The prognosis for patients with the onset of Legg-Calvé-Perthes disease before the age of six years is favorable, with 80% having a good result.
Legg-Calvé-Perthes disease. The prognostic significance of the subchondral fracture and a two-group classification of the femoral head involvement.
- MedicineThe Journal of bone and joint surgery. American volume
- 1984
A simple and practical two-group classification of the extent of involvement of the femoral head is proposed: Group A (less than half of the head) and Group B (more than half the head).
Perthes' disease in the adolescent.
- MedicineThe Journal of bone and joint surgery. British volume
- 2001
The poorest clinical results were found in the destructive type which was frequently associated with incapacitating pain requiring arthrodesis or excision arthroplasty within three years of onset of the disease.
Biomechanical properties of bone and cartilage in growing femoral head following ischemic osteonecrosis
- MedicineJournal of orthopaedic research : official publication of the Orthopaedic Research Society
- 2007
Results indicate that the deterioration of the mechanical properties of the epiphyseal bone and cartilage likely plays a significant role in the pathogenesis of the femoral head deformity in LCPD.
Arthrodiastasis in Perthes' disease. Preliminary results.
- MedicineThe Journal of bone and joint surgery. British volume
- 2004
The primary outcome measure was the extent of epiphyseal collapse at the end of the fragmentation phase, which included pin-site infection in most hips, transient joint stiffness in two, and breakage of a pin in two.
Incidence of Legg-Perthes disease (osteochondritis deformans).
- MedicineThe New England journal of medicine
- 1966
Estimation of incidence and attack rates in a defined population of children resident in Massachusetts in whom the diagnosis of Legg–Perthes disease was made for the first time during 1964 is attempted.