Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s

  title={Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s},
  author={Peter D. Weinberg and Jennie Hounshell and Laurence A. Sherman and John R Godwin and Shirin Ali and Cec{\'i}lia Tomori and Charles L. Bennett},
  journal={Annals of Internal Medicine},
During the onset of the AIDS epidemic in 1981, persons with hemophilia and blood-transfusion recipients throughout the world became infected with HIV through transfusion of contaminated blood products (1-7) (Table 1). In 1982, 1 year after the first AIDS cases were reported, the U.S. Centers for Disease Control and Prevention suggested that the syndrome was associated with blood and blood products (11, 12). Table 1. Persons with Hemophilia Who Developed HIV Infection from Transfusion of… 

Current and emerging infectious risks of blood transfusions.

Pathogen reduction methods, already successfully applied to pooled plasma derivatives (eg, albumin, clotting factor concentrates, immunoglobulin preparations) are now in development for cellular blood components and fresh-frozen plasma, which could virtually eliminate the risk of transmission by transfusions of both known and emerging infectious agents in technologically advanced countries.

Transfusion-associated HIV infection in Mexico related to paid blood donors; HIV epidemic.

A well-defined epidemic period of HIV-infection among blood-recipients was identified that coincided with the HIV-epidemic among paid donors and TAHI patients in Mexico developed AIDS in a shorter time than that described for other populations.

The AIDS epidemic in haemophilia patients II: pursuing absolute viral safety of clotting factor concentrates 1985–1988

  • B. Evatt
  • Medicine
    Haemophilia : the official journal of the World Federation of Hemophilia
  • 2012
The period from 1985 to 1990 was a period of uncertainty about clinical safety and the haemophilia community, the treating physicians, the manufacturers of coagulation products and regulatory agencies had to make difficult decisions about the reliability of products, manufacturing practices and therapeutic choices with little guidance.

A Full-Blown Epidemic

Safety of the Blood Supply in Latin America

SUMMARY Appropriate selection of donors, use of sensitive screening tests, and the application of a mandatory quality assurance system are essential to maintain the safety of the blood supply. Laws,

Claims and compensation for complications resulting from blood transfusions in China from 1998 to 2013.

  • Heng LiXiaowen ZhaoWenhui LiHong Zhao
  • Medicine
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
  • 2015

Paid donation and plasma trade: unrecognized forces that drive the AIDS epidemic in developing countries

The commercial plasma industry and blood trade can fuel the transmission of HIV in a community by the most efficient way in which HIV is transmitted: the parenteral route. Paid donors get infected at

Social consequences of infected haemophilia cases in the Islamic Republic of Iran.

  • A. CheraghaliP. EshghiH. Abolghasemi
  • Medicine, Political Science
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
  • 2011
The unintentional contamination of haemophilia patients with HIV in the early 1980s raised serious questions about the safety of blood product supplies worldwide and the adverse consequences on the equitable distribution of resources in the Iranian health care system are discussed.



HIV and the blood supply: an analysis of crisis decision making.

This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system.

Safety of the Blood Supply in the United States: Opportunities and Controversies

This work considered ongoing efforts to improve transfusion safety and some of their potential consequences, and considered whether a zero-risk blood supply remains a popular goal.

Do Institutions Matter: A Comparative Pathology of the HIV-Infected Blood Tragedy

The introduction of HIV (human immunodeficiency virus) into the blood systems of many different countries, developed and developing, during the late 1970s and early 1980s and its subsequent

The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study.

The risk of transmitting HIV, HTLV, HCV, or HBV infection by the transfusion of screened blood is very small, and new screening tests will reduce the risk even further.

Blood transfusion practices in India: results of a national survey.

Testing for transfusion-transmitted infections is unsatisfactory and poorly regulated in India and Reporting of adverse events after transfusion is poor and no stringent donor deferral system exists.

Blood safety decisions, 1982 to 1986: perceptions and misconceptions

The Report may accurately reflect the testimony heard, but it is biased by the committee's acceptance as fact the opinions of critics who claim the AIDS epidemic was mismanaged by the blood-collecting agencies, professional organizations, hemophilia organizations, and the federal government.

Blood transfusion practices and blood-banking services in a Kenyan hospital.

Improved laboratory services, reduction of unnecessary transfusions, and increased recruitment of volunteer donors are critical for improving the appropriate and timely use of blood and reducing transfusion-associated HIV transmission.

Residues of NAT:questions and commentary

  • L. Sherman
  • Medicine, Political Science
  • 2000
The effectiveness of various steps in NAT implementation and the historical background of previous introduction of new tests are focused on, and the program is considered in light of recent shifts in the ethical role of medical professionals, both private and governmental.

HIV and Canada's hemophiliacs: looking back at a tragedy.

  • K. Dunn
  • Medicine
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • 1993
Canadian hemophiliacs have not reacted with the vehemence of their French counterparts, 1000 of whom insisted that criminal charges be laid against those responsible for France's blood supply: * The Canadian Hemophilia Society was at the table with government representatives and the Red Cross in 1984 when crucial decisions were made about the blood supply and the threat posed by possible HIV contamination.

A crucial role for B cells in neuroinvasive scrapie.