Leg ulceration in sickle cell disease: medieval medicine in a modern world.

@article{Serjeant2005LegUI,
  title={Leg ulceration in sickle cell disease: medieval medicine in a modern world.},
  author={Graham R. Serjeant and Beryl E. Serjeant and Junette S Mohan and Andrea Clare},
  journal={Hematology/oncology clinics of North America},
  year={2005},
  volume={19 5},
  pages={943-56, viii-ix}
}
Leg ulceration is now recognized as an important complication of sickle cell disease, especially of the SS genotype. Since there is no convincing evidence of delayed healing of operation scars or of wounds elsewhere in the body, it must be concluded that factors specific to the lower leg render patients prone to delayed healing at this site. Many lesions are traumatic in origin and since there is considerable variation in healing rates among the normal population, it is useful to define chronic… CONTINUE READING

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