Left ventricular volume measurement in mice by conductance catheter: evaluation and optimization of calibration.

@article{Nielsen2007LeftVV,
  title={Left ventricular volume measurement in mice by conductance catheter: evaluation and optimization of calibration.},
  author={Jan M\oller Nielsen and Steen Buus Kristiansen and Steffen Ringgaard and Torsten Toftegaard Nielsen and Allan Flyvbjerg and Andrew N Redington and Hans Erik B\otker},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={293 1},
  pages={H534-40}
}
The conductance catheter (CC) allows thorough evaluation of cardiac function because it simultaneously provides measurements of pressure and volume. Calibration of the volume signal remains challenging. With different calibration techniques, in vivo left ventricular volumes (V(CC)) were measured in mice (n = 52) with a Millar CC (SPR-839) and compared with MRI-derived volumes (V(MRI)). Significant correlations between V(CC) and V(MRI) [end-diastolic volume (EDV): R(2) = 0.85, P < 0.01; end… CONTINUE READING

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