Left ventricular underfilling and not septal bulging dominates abnormal left ventricular filling hemodynamics in chronic thromboembolic pulmonary hypertension.

@article{Lumens2010LeftVU,
  title={Left ventricular underfilling and not septal bulging dominates abnormal left ventricular filling hemodynamics in chronic thromboembolic pulmonary hypertension.},
  author={Joost Lumens and Daniel G. Blanchard and Theo Arts and Ehtisham Mahmud and Tammo Delhaas},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2010},
  volume={299 4},
  pages={H1083-91}
}
Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with abnormal left ventricular (LV) filling hemodynamics [mitral early passive filling wave velocity/late active filling wave velocity (E/A) < 1]. Pulmonary endarterectomy (PEA) acutely reduces pulmonary vascular resistance, resulting in an increase of mitral E/A. The abolishment of leftward septal bulging and an increase in right ventricular (RV) output are thought to be responsible for the increase of mitral E/A. In this… CONTINUE READING
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