Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure.

@article{Kono1992LeftVS,
  title={Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure.},
  author={Tatsuji Kono and Hani N. Sabbah and Howard Seeman Rosman and Mahbubul Alam and Syed Khurram Ali Jafri and Sidney Goldstein},
  journal={Journal of the American College of Cardiology},
  year={1992},
  volume={20 7},
  pages={1594-8}
}
OBJECTIVES The aim of this study was to examine the temporal association between the onset of functional mitral regurgitation and the development of changes in left ventricular shape, chamber enlargement, mitral anulus dilation and regional wall motion abnormalities during the course of evolving heart failure. BACKGROUND Despite extensive characterization, the exact etiology of functional mitral regurgitation in patients with chronic heart failure remains unknown. METHODS Heart failure was… CONTINUE READING
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