Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect?

@article{Weir2009LeftVR,
  title={Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect?},
  author={Robin A. P. Weir and Patrick B Mark and Colin Petrie and Suzanne E Clements and Tracey Steedman and Ian Ford Ford and Leong Loke Ng and Iain B Squire and Galen S. Wagner and John J V McMurray and Henry J. Dargie},
  journal={American heart journal},
  year={2009},
  volume={157 6},
  pages={1088-96}
}
AIMS Aldosterone antagonism reduces cardiovascular morbidity and mortality in patients with left ventricular (LV) systolic dysfunction and heart failure or diabetes after acute myocardial infarction (AMI). The mechanism of this effect is unclear. We performed a contrast-enhanced cardiac magnetic resonance study to assess the effects of eplerenone on LV remodeling after AMI. METHODS One hundred patients (mean age, 58.9 +/- 12 years; 77% male) with LV systolic dysfunction but without heart… CONTINUE READING

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