Left ventricular insulin-like growth factor I increases in early renal hypertension.

  title={Left ventricular insulin-like growth factor I increases in early renal hypertension.},
  author={H{\aa}kan W{\aa}hlander and Jorgen Isgaard and Eva Jennische and Peter Friberg},
  volume={19 1},
Increasing interest has been directed toward the possible role of trophically acting molecules as modulators or initiators, or both, of myocardial hypertrophy. The aim of the present study was to investigate the possible role of one such molecule, namely, insulin-like growth factor I, in myocardial hypertrophy developed in response to renal artery stenosis. Two-kidney, one clip Goldblatt hypertension was induced in Wistar rats weighing 180 g, and sham-operated animals were used as controls… CONTINUE READING


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