Left ventricular endocardial or triventricular pacing to optimize cardiac resynchronization therapy in a chronic canine model of ischemic heart failure.

@article{Bordachar2012LeftVE,
  title={Left ventricular endocardial or triventricular pacing to optimize cardiac resynchronization therapy in a chronic canine model of ischemic heart failure.},
  author={Pierre Bordachar and Nathan A Grenz and Pierre Ja{\"i}s and Philippe Ritter and Christophe Leclercq and John M. Morgan and Daniel Cabeza Gras and Ping Yang},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2012},
  volume={303 2},
  pages={
          H207-15
        }
}
Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure but ~30% of patients appear to not benefit from the therapy. Left ventricular (LV) endocardial and multisite epicardial [triventricular (TriV)] pacing have been proposed as alternatives to traditional LV transvenous epicardial pacing, but no study has directly compared the hemodynamic effects of these approaches. Left bundle branch block ablation and repeated microembolizations were performed in dogs to induce… CONTINUE READING

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