Left ventricular dysfunction in Klinefelter syndrome is associated to insulin resistance, abdominal adiposity and hypogonadism.

@article{Andersen2008LeftVD,
  title={Left ventricular dysfunction in Klinefelter syndrome is associated to insulin resistance, abdominal adiposity and hypogonadism.},
  author={Niels Holmark Andersen and Anders Bo Bojesen and Kurt Kristensen and Niels H Birkebaek and Jens Fedder and Paul Bennett and Jens Sandahl Christiansen and Claus H\ojbjerg Gravholt},
  journal={Clinical endocrinology},
  year={2008},
  volume={69 5},
  pages={785-91}
}
OBJECTIVE Epidemiological data suggest there is an increased risk of dying from heart disease among patients with Klinefelter syndrome (KS). Due to high prevalence of hypogonadism and metabolic syndrome, we speculated that patients with KS may have subclinical changes in the left ventricular function. Therefore, the aim was to assess left ventricular long axis function by tissue Doppler echocardiography in patients with KS and relate these findings to the metabolic status and testosterone… CONTINUE READING

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