Left ventricular-arterial coupling in conscious dogs.

  title={Left ventricular-arterial coupling in conscious dogs.},
  author={William James Little and C P Cheng},
  journal={The American journal of physiology},
  volume={261 1 Pt 2},
We investigated the criteria for the coupling of the left ventricle (LV) and the arterial system to maximize LV stroke work (SW) and the transformation of LV pressure-volume area (PVA) to SW. We studied eight conscious dogs that were instrumented to measure LV pressure and determine LV volume from three ultrasonically determined dimensions. The LV end-systolic pressure (PES)-volume (VES) relation was determined by caval occlusion. Its slope (EES) was compared with the arterial elastance (EA… CONTINUE READING


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