Left ventricular adaptation to aortic regurgitation in conscious dogs.

  title={Left ventricular adaptation to aortic regurgitation in conscious dogs.},
  author={J. William Gaynor and Michael P. Feneley and Scott A. Gall and Michael A Savitt and Scott C. Silvestry and James Wayne Davis and James S. Rankin and Donald D. Glower},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={113 1},
OBJECTIVE Cardiac failure as a result of valvular heart disease remains a major clinical problem that frequently leads to ventricular dysfunction, myocardial failure, and even death. The development of irreversible myocardial damage may be especially insidious in volume overload as a result of aortic or mitral regurgitation. METHODS AND RESULTS Left ventricular wall volume, ventricular function, and myocardial performance were assessed in 10 chronically instrumented conscious dogs before and… CONTINUE READING