Left frontotemporal hypoperfusion is associated with aggression in patients with dementia.

@article{Hirono2000LeftFH,
  title={Left frontotemporal hypoperfusion is associated with aggression in patients with dementia.},
  author={Nobutsugu Hirono and Michael S. Mega and Ivo D. Dinov and Fred Mishkin and Jeffrey L. Cummings},
  journal={Archives of neurology},
  year={2000},
  volume={57 6},
  pages={861-6}
}
BACKGROUND Aggressive behavior is common in patients with dementia. Temporolimbic and prefrontal cortical lesions can produce pathological aggression; however, involvement of these structures has not been established in aggressive patients with dementia. OBJECTIVE To study the relation between regional brain perfusion and aggressive behavior in patients with dementia. METHODS We compared the pattern of regional cerebral perfusion determined with technetium Tc 99m-labeled hexamethylpropelene… CONTINUE READING

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Orbital frontal and anterior cingulate pretreatment perfusion defects on 99mTc-HMPAOSPECT are associated with behavioral response to cholinesterase inhibitor therapy in Alzheimer’s disease

  • MS Mega, SM O’Connor, L Lee, ID Dinov, JL Cummings, AW. Toga
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