Left atrial dysfunction as a determinant of pulmonary hypertension in patients with severe aortic stenosis and preserved left ventricular ejection fraction

@article{Clin2017LeftAD,
  title={Left atrial dysfunction as a determinant of pulmonary hypertension in patients with severe aortic stenosis and preserved left ventricular ejection fraction},
  author={Andreea Călin and Anca Doina Mateescu and Monica Roşca and Carmen Cristiana Beladan and Roxana Enache and Simona Botezatu and Iulian Cosei and Cosmin Calin and Marian Simion and Carmen Doina Ginghină and Andreea Popescu and Bogdan Popescu},
  journal={The International Journal of Cardiovascular Imaging},
  year={2017},
  volume={33},
  pages={1939-1947}
}
In patients with severe aortic stenosis (AS), the presence of pulmonary hypertension (PH) has been linked to a poor prognosis. We aimed to assess the main determinants of PH in patients with severe AS and preserved left ventricular ejection fraction (LVEF). We prospectively enrolled 108 consecutive patients with isolated severe AS (indexed aortic valve area <0.6 cm2/m2) and LVEF >50%, in sinus rhythm. Left atrial (LA) function was assessed using longitudinal deformation parameters (by speckle… CONTINUE READING
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