Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.

@article{Whitlock2021LeftAA,
  title={Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.},
  author={Richard Paul Whitlock and Emilie P. Belley-C{\^o}t{\'e} and Domenico Paparella and Jeff S. Healey and Katheryn Brady and Mukul Sharma and Wilko Reents and Petr Budera and Andony J Baddour and Petr Fila and P J Devereaux and Alexander V Bogachev-Prokophiev and Andreas Boening and Kevin H. T. Teoh and Georgios I. Tagarakis and Mark S. Slaughter and Alistair G. Royse and Shay P. McGuinness and Marco Alings and Prakash P Punjabi and C. David Mazer and Richard J Folkeringa and Andrea Colli and {\'A}lvaro Avezum and Juliet Nakamya and Kumar Balasubramanian and Jessica Vincent and Pierre Voisine and Andr{\'e} Lamy and Salim Yusuf and Stuart J. Connolly},
  journal={The New England journal of medicine},
  year={2021}
}
BACKGROUND Surgical occlusion of the left atrial appendage has been hypothesized to prevent ischemic stroke in patients with atrial fibrillation, but this has not been proved. The procedure can be performed during cardiac surgery undertaken for other reasons. METHODS We conducted a multicenter, randomized trial involving participants with atrial fibrillation and a CHA2DS2-VASc score of at least 2 (on a scale from 0 to 9, with higher scores indicating greater risk of stroke) who were scheduled… 

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TLDR
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