Leflunomide therapy for polyomavirus-induced allograft nephropathy: efficient BK virus elimination without increased risk of rejection.

@article{Teschner2009LeflunomideTF,
  title={Leflunomide therapy for polyomavirus-induced allograft nephropathy: efficient BK virus elimination without increased risk of rejection.},
  author={Sven Teschner and Peter Gerke and Marcel Geyer and Jochen Wilpert and Bernd Krumme and Thomas Benzing and Gerd Walz},
  journal={Transplantation proceedings},
  year={2009},
  volume={41 6},
  pages={2533-8}
}
BACKGROUND Optimal treatment of polyomavirus-induced allograft nephropathy (PVAN) with immunosuppressive and antiviral therapy is uncertain at present. Reduced immunosuppression is accompanied by increased risk of rejection, and antiviral agents are nephrotoxic. Leflunomide has immunosuppressive and antiviral properties and may be an alternative treatment agent. We report a two-center experience with use of leflunomide for treatment of PVAN. PATIENTS AND METHODS Thirteen renal allograft… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 14 references

Leflunomide treat - ent for polyomavirus BK – associated nephropathy after kidney ransplantation

  • P Randhawa, A Ho, R Shapiro
  • Transpl Int
  • 2007

: interdisciplinary nalyses and recommendations

  • C Drachenberg, J Papadimitriou, H Hirsch
  • 2005

Leflunomide for olyomavirus type BK nephropathy

  • S Teschner, M Geyer, J Wilpert
  • N Engl J Med
  • 2005

Histolog - cal patterns of polyomavirus nephropathy : correlation with graft utcome and viral load

  • B Vasudev, S Hariharan, SA Hussain
  • Am J Transplant
  • 2004

Clinical ourse of polyomavirus nephropathy in 67 renal transplant pa - ients

  • JW Williams, B Javaid, PV Kadambi
  • J Am Soc Nephrol
  • 2002

Prospective tudy of polyomavirus type BK replication and nephropathy in enal - transplant recipients

  • E Ramos, CB Drachenberg, JC Papadimitriou
  • N Engl J Med
  • 2002

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