Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients.

@article{Ishaq2011LeflunomideOM,
  title={Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients.},
  author={Mohammad G Ishaq and Jibran Sualeh Muhammad and K. N. Shahul Hameed and Ahmad Iqbal Mirza},
  journal={Modern rheumatology},
  year={2011},
  volume={21 4},
  pages={
          375-80
        }
}
In order to compare the efficacy and toxicity of methotrexate and leflunomide for the treatment of rheumatoid arthritis, a double-blind randomized clinical trial was carried out at the Department of Medicine, Jinnah Medical College Hospital, Korangi, Karachi. The sample size was 240 patients and the duration of the study was 1 year. The patients enrolled were randomly divided into two groups (methotrexate and leflunomide). RA activity was clinically assessed by noting changes in the four… CONTINUE READING
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