Leech Retzius cells and 5-hydroxytryptamine.

  title={Leech Retzius cells and 5-hydroxytryptamine.},
  author={Lucy D. Leake},
  journal={Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology},
  volume={83 2},
  • Lucy D. Leake
  • Published 1986 in
    Comparative biochemistry and physiology. C…
A pair of giant Retzius (R) cells in each segmental ganglion of the leech contain 5-hydroxytryptamine (5-HT). They are the only 5-HT-containing neurones in the central nervous system to send branches to the periphery, yet many peripheral tissues (e.g. body wall muscles, heart, reproductive organs, nephridia and gut) possess 5-HT-like immunoreactive nerve fibres. 5-HT and/or R cell stimulation relax basal tension of body wall muscles and reduce their relaxation times following contraction… CONTINUE READING

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