Lectin-induced damage to the enterocyte brush border. An electron-microscopic study in rabbits.


The ultrastructural effects of 11 lectins on the intestinal brush border were examined by means of an in vitro rabbit ileal mucosal explant culture system. Five of the lectins that bind to oligosaccharides containing either N-acetylglucosamine (phytohaemagglutinin, Euonymus europaeus lectin, pokeweed mitogen, and wheat germ agglutinin) or N-acetylneuraminic… (More)


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