Lectin-binding properties of human breast cancer cell lines and human milk with particular reference to Helix pomatia agglutinin.

@article{Schumacher1995LectinbindingPO,
  title={Lectin-binding properties of human breast cancer cell lines and human milk with particular reference to Helix pomatia agglutinin.},
  author={Udo Schumacher and Elizabeth Adam and Susan Ann Brooks and Anthony J. C. Leathem},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1995},
  volume={43 3},
  pages={275-81}
}
Several studies have shown binding of a variety of lectins to breast cancer cells in tissue sections. In particular, binding of the lectin from the Roman snail, Helix pomatia agglutinin (HPA), to breast cancer cells is linked with a poor prognosis. The molecular basis for lectin binding to metastatic breast cancers is not known. To elucidate this in a model system, lectin-binding patterns of seven human breast cancer cell lines were investigated, their cell membranes were isolated, and HPA… CONTINUE READING

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