Lecithin cholesterol acyltransferase.

  title={Lecithin cholesterol acyltransferase.},
  author={Ana Jonas},
  journal={Biochimica et biophysica acta},
  volume={1529 1-3},
  • Ana Jonas
  • Published 2000 in Biochimica et biophysica acta
Cholesterol transport in circulation and its removal from tissues depends on the activity of lecithin cholesterol acyltransferase (LCAT). LCAT is a soluble enzyme that converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lyso-phosphatidylcholines on the surface of high-density lipoproteins. This review presents key background information and recent research advances on the structure of human LCAT, its reactions and substrates, and the expression of the LCAT gene… CONTINUE READING

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