Leber’s Hereditary Optic Neuropathy associated with cocaine, ecstasy and telithromycin consumption


Sirs: Leber’s hereditary optic neuropathy (LHON) is a matrilinear disorder characterised by acute to subacute bilateral optic neuropathy, mostly affecting young males at variable age of onset. More than 90% of patients harbour one of the three pathogenic mitochondrial DNA (mtDNA) mutations: 3,460, 11,778, and 14,484, all in genes encoding subunits of… (More)
DOI: 10.1007/s00415-006-0351-4


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