Leber's hereditary optic neuropathy masquerading as tobacco-alcohol amblyopia.

Abstract

OBJECTIVE To determine the frequency of known primary mitochondrial DNA (mtDNA) mutations for Leber's hereditary optic neuropathy (LHON) in patients previously diagnosed as having tobacco-alcohol amblyopia. DESIGN A case series of 12 patients with tobacco-alcohol amblyopia. Follow-up ranged from 2 months to 15 years. SETTING Tertiary care. PATIENTS… (More)

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