Learning score function parameters for improved spectrum identification in tandem mass spectrometry experiments.

Abstract

The identification of proteins from spectra derived from a tandem mass spectrometry experiment involves several challenges: matching each observed spectrum to a peptide sequence, ranking the resulting collection of peptide-spectrum matches, assigning statistical confidence estimates to the matches, and identifying the proteins. The present work addresses… (More)
DOI: 10.1021/pr300234m

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Cite this paper

@article{Spivak2012LearningSF, title={Learning score function parameters for improved spectrum identification in tandem mass spectrometry experiments.}, author={Marina Spivak and Michael Bereman and Michael J. MacCoss and William Stafford Noble}, journal={Journal of proteome research}, year={2012}, volume={11 9}, pages={4499-508} }