Learning-related translocation of δ-opioid receptors on ventral striatal cholinergic interneurons mediates choice between goal-directed actions.

@article{BertranGonzalez2013LearningrelatedTO,
  title={Learning-related translocation of δ-opioid receptors on ventral striatal cholinergic interneurons mediates choice between goal-directed actions.},
  author={Jesus Bertran-Gonzalez and Vincent Laurent and Billy C H Chieng and Macdonald J Christie and Bernard W. Balleine},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2013},
  volume={33 41},
  pages={16060-71}
}
The ability of animals to extract predictive information from the environment to inform their future actions is a critical component of decision-making. This phenomenon is studied in the laboratory using the pavlovian-instrumental transfer protocol in which a stimulus predicting a specific pavlovian outcome biases choice toward those actions earning the predicted outcome. It is well established that this transfer effect is mediated by corticolimbic afferents on the nucleus accumbens shell (NAc… CONTINUE READING
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lamic gating of corticostriatal signaling by cholinergic interneurons

  • L Faget, E Erbs, +10 authors BL Kieffer
  • 2012
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